Bridging Polycystic Ovarian Syndrome and Periodontitis: A Review of Oral-systemic Health Interactions
Suganthi R *
Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth (Deemed to be University), Pillaiyarkuppam, Puducherry – 607402, India.
R. Saravana Kumar
Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth (Deemed to be University), Pillaiyarkuppam, Puducherry – 607402, India.
Pratebha B
Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth (Deemed to be University), Pillaiyarkuppam, Puducherry – 607402, India.
Narayane R
Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth (Deemed to be University), Pillaiyarkuppam, Puducherry – 607402, India.
*Author to whom correspondence should be addressed.
Abstract
Polycystic ovary syndrome (PCOS) is a multifaceted condition that impacts hormonal balance, fertility, and metabolic function, influencing around 5–15% of women worldwide. Periodontitis (PD) is a persistent inflammatory disease with multiple contributing factors, triggered by a dysbiotic dental plaque, leading to the breakdown of the periodontium—the supporting structures of the teeth. It has been suggested that there may be a bidirectional connection between PCOS and periodontal diseases. Both conditions share common risk factors such as chronic systemic inflammation, insulin resistance, and oxidative stress. Periodontal diseases are worsened by Chronic mild inflammation linked to PCOS encompasses factors such as excess body weight, ongoing immune dysregulation, and elevated oxidative stress. Thus, this review will concentrate on the connection between PCOS and periodontal diseases, along with the shared risk factors for both conditions.
Keywords: Insulin resistance, systemic inflammation, PCOS, oxidative stress, periodontal disease