A Clinical Trail of Silver Diamine Fluoride Application on Children’s Primary Teeth to Arrested Carious Lession among Preschool Children, Vientiane: A Pilot Study
Published: 2024-07-04
Page: 224-232
Issue: 2024 - Volume 7 [Issue 1]
Amphayvan Homsavath *
Faculty of Dentistry, University of Health Sciences, Lao PDR.
Mayfong Mayxay
University of Health Sciences, Lao PDR.
Viraseang Rajpho
Faculty of Medical, University of Health Sciences, Lao PDR.
Souksida Xaykhamban
Faculty of Dentistry, University of Health Sciences, Lao PDR.
Chanvilay Soukkhaseum
Faculty of Dentistry, University of Health Sciences, Lao PDR.
Phimfalee Sayyaxang
Faculty of Dentistry, University of Health Sciences, Lao PDR.
Viengsavanh Inthakoun
Faculty of Dentistry, University of Health Sciences, Lao PDR.
Souliyo Souvong
Faculty of Dentistry, University of Health Sciences, Lao PDR.
Patay Vongsathien
Faculty of Dentistry, University of Health Sciences, Lao PDR.
Vimonh Thongterm
Faculty of Dentistry, University of Health Sciences, Lao PDR.
Thongsavan Vetsouvanh
Faculty of Dentistry, University of Health Sciences, Lao PDR.
Phetlamphay Sidanoumonh
Faculty of Dentistry, University of Health Sciences, Lao PDR.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Recent studies indicate a double increase of the prevalence and severity of Early Child Dental Caries (ECC) in Vientiane.
Aim: This study is to deliver Silver diamine fluoride (SDF) to prevent dental caries progression among children who attending Pre-school in Vientiane Capital.
Methods: Children was having an oral examination for dental caries using the Caries Assessment Spectrum and Treatment (CAST) index. Only the children with caries lesions in enamel and dentine was receive SDF. An evaluation of SDF was occurred after three months fellow-up between intervention and control group. A 24-hr phone call/whatapp was be implemented to address any concerns or clinical events after SDF application and before the follow-up time. Chi-square or student T-test was used to compare caries status against sociodemographic characteristics, parents’ acceptance, and caries status.
Results: A total of 400 children, mean age was 4.3 [0.8] year. In baseline, 77.8 % reported dental caries in intervention group and 74.4% in control group, there were increasing of prevalence dental caries in control group 84.3% and 74.2% in intervention group after 3 month follow up (p=0.045). Furthermore, after 3 months follow up, there is little change in the control group on mean number of decayed enamel or decayed dentin. However, the mean number of deep lesions increased from 0.74 to 1.13 pulp lesions from 0.64 to 0.82, and soft-tissue lesions. In the intervention group, the mean number of decayed enamel decreased from 1.80 to 1.11, decayed dentin decreased from 2.37 to 1.07. That because of the carious lesion arrested to enamel and dentin. There was statistically significant p=0.001. The postoperative sign and symptoms and satisfied from parental after apply Silver Diamine Fluoride is good report for initial to use SDF controlling of dental caries progression.
Conclusion: The study provide information of SDF treatment can be prevent and controlling caries progress in children due to ECC high prevalence, the effectives of SDF treatment to prevent dental caries, long term follow up is needed and necessary for evidence of effectiveness with low cost.
Keywords: ECC, SDF, caries arrested, CAST
How to Cite
References
Chanthaphone V. Dental Caries and its impact on quality of life among children age 12-60 months and their families in nursery and kindergarten schools in Vientiane Capital Lao PDR, 2021 Lao Library; 2022.
Gisele AC, Natália AAG, Lídia Audrey RV, Edilson Martins RN, Fernanda Matias C, Fernanda LD, Sale P, Patrícia Leal DL, Quality of life assessment of children with early childhood caries in a Brazilian City J Young Pharm. 2021;13(3): 270-273
Gumro, Menia, Sonal Gupta, Maadhukar Yadav, and Asmita Das. 2022. Smile design in pediatric dentistry: A case series. International Journal of Research and Reports in Dentistry. 2022;5(2):137-43. Available:https://journalijrrd.com/index.php/IJRRD/article/view/123
Clemens J, Gold J, Chaffin J. Effect and acceptance of silver diamine fluoride treatment on dental caries in primary teeth. Journal of Public Health Dentistry. 2018;78(1):63-8.
Zhao IS, Gao SS, Hiraishi N, Burrow MF, Duangthip D, Mei ML, Lo EC, Chu CH. Mechanisms of silver diamine fluoride on arresting caries: A literature review. International Dental Journal. 2018;68(2): 67-76.
Violeta C, Milagros JT. Toro, Augusto R. Elías-Boneta, Angeliz EB, Effectiveness of silver diamine fluoride in caries prevention and arrest: a systematic literature review”. Published with permission of the Academy of General Dentistry. © Copyright 2017 by the Academy of General Dentistry, please contact rhondab@fosterprinting.com; 2017.
Laura Timms, Sumner O, Deery C, Rogers H. “Everyone else is using it, so why isn't the UK? Silver diamine fluoride for children and young people Community Dental Health. 2020;37(2). DOI: 10.1922/CDH_00008Timms07
Christine Frank, Tim Jewell; Medically reviewed Silver Diamine Fluoride Updated. 2018;6.
Horst JA, Ellenikiotis H, Milgrom PL. UCSF protocol for caries arrest using silver diamine fluoride: Rationale, indications and consent. J CalifDent Assoc. 2016;44(1):16-28
Ryan Richard Ruff, Deepak Saxenaand Richard Niederman “School-based caries prevention and longitudinal trends in untreated decay: An updated analysis with Marcov chains” Ruff et al. BMC Res Notes. 2020;13:25. Available:https://doi.org/10.1186/s13104-020-4886-8
Ana L. de Souza, Wil J.M. Van der Sanden, Soraya C. Leal, Jo E. Frencken, “The Caries Assessment Spectrum and Treatment (CAST) index: face and content validation. International Dental Journal. 2012;62(5):270-276
Yamaga R, Yokomizo I. Arrestment of caries of deciduous teeth with diamine silver fluoride treatment on dental caries. Dent Outbook. 1969;33:1007-13
Yasmi O. Crystal, Richard Niederman. Evidence-Based Dentistry Update on Silver Diamine Fluoride. Dent Clin North Am. Author manuscript; available in PMC 2020 Jan 1 Dent Clin North Am. 2019; 63(1):45–68.
Marcus HT Fung, May CM Wong, Edward CM Lo, CH Chu. Arresting early childhood caries with silver diamine fluoride-a literature review. Journal of Oral Hygiene and Health. 2013;1(3). article no. 1000117. DOI: http://dx.doi.org/10.4172/2332-0702.1000117.
World Health Organization. “Oral health surveys: Basic methods - 5th edition”; 2013,
Nishino M, Yoshida S, Sobue S, Kato J., Nishida M. Effect of topically applied ammoniacal silver fluoride on dental caries in children. J. Osaka Univ. Dent. Sch. 1969;9:149–155.
Mei ML., Lo E.C.M., Chu C.H. Clinical Use of Silver Diamine Fluoride in Dental Treatment. Compend. Contin. Educ. Dent. 2016;37:93–98.
FDA Regulated Prescription Medical Device and Is Only Available For Purchase And Administration By A Licensed Healthcare Professional. Available:https://dentaquick.com/en/ products/ elevate-oral-care-releases-advantage-arrest-silver-diamine-fluoride
World Health Organization (WHO) List of Essential Medicines (EML).; 2023. (Accessed on 3 January 2023).
Tirupathi SP, Svsg N, Rajasekhar S, Nuvvula S. Comparative cariostatic efficacy of a novel Nano-silver fluoride varnish with 38% silver diamine fluoride varnish a double-blind randomized clinical trial. J. Clin. Exp. Dent. 2019;11:e105–e112. DOI: 10.4317/jced.54995
Mabangkhru S., Duangthip D., Chu C.H., Phonghanyudh A., Jirarattanasopha V. A randomized clinical trial to arrest dentin caries in young children using silver diamine fluoride. J. Dent. 2020;99:103375. DOI: 10.1016/j.jdent.2020.103375.
Vollú AL, Rodrigues GF, Teixeira RVR, Cruz LR, Massa GDS, Moreira JPDL, Luiz RR, Barja-Fidalgo F, Fonseca-Gonçalves A. Efficacy of 30% silver diamine fluoride compared to atraumatic restorative treatment on dentine caries arrestment in primary molars of preschool children: A 12-months parallel randomized controlled clinical trial. J. Dent. 2019;88: 103165. DOI: 10.1016/j.jdent.2019.07.003
Aparna C, Sushma G. Evaluation of the clinical efficacy of 38% silver diamine fluoride in arresting dental caries in primary teeth and its parental acceptance. Journal of Indian; 2022, IP: 202.62.99.233
Crystal Yo, Marghalani AA, Ureless SD, Wright JT, Sulyanto R, Divaris K. “Use of Silver Diamine Fluoride for Dental caries management in children and adolescents, including Those with special health cares. Pediatr Dent. 2017;39(5):135-145.
Duangthip D, Fung MHT, Lo ECM. Adverse Effects of Silver Diamine Fluoride Treatment among Preschool Children. 2017;97:4, Available:https://doi.org/10.1177/002203 4517746678.
Gordon NB. Silver diamine fluoride staining is acceptable for posterior primary teeth and is preferred over advanced pharmacologic behavior management by many parents. Evid Based Dent Pract. 2018;18:18949-1897.
Rutchada K, Kemporn K, Waranuch P, Ananda PD, Patimaporn P. Parent-child Satisfaction and safety of Silver Diamine Fluoride and Fluoride Varnish Treatment. The International Journal of Oral Health. 2018;14:52-63,.
Sara M Bagher, Heba J Sabbagh, Samer M Aljohani, Gahida Ajharbi, Heba Elkhodary. “Parental acceptance of the utilization of silver diamine fluoride on their child’s primary and permanent teeth”. Original Research, Patient Preference and Adherence. 2019:13: 829-835.
Branca HO, Anjana R, Analia VK, Richard N. “The effect of silver diamine fluoride in preventing caries in the primary dentition: A systematic review and meta-analysis. Caries Research. 2019;53:24-32. DOI:10.1159/000488686