The Role of Revascularization in Saving and Restoring Teeth – A Comprehensive Review
Published: 2024-06-17
Page: 204-216
Issue: 2024 - Volume 7 [Issue 1]
Suraiya Taranum *
Department of Conservative Dentistry and Endodontics, DAPM RV Dental College Bangalore, India.
Rashmi G Shetty
Department of Conservative Dentistry and Endodontics, DAPM RV Dental College Bangalore, India.
Keshava Prasad
Department of Conservative Dentistry and Endodontics, DAPM RV Dental College Bangalore, India.
Suman C
Department of Conservative Dentistry and Endodontics, DAPM RV Dental College Bangalore, India.
*Author to whom correspondence should be addressed.
Abstract
Pulp regeneration may be defined as the replacement of damaged tissue by cells identical to the lost tissue, leading to the complete reestablishment of biological function. Using revascularization procedures to induce apexogenesis and subsequently tissue regeneration, instead of replacing tissue with artificial substitutes, is a relatively new therapeutic modality for young teeth with non-vital pulp Revascularization/revitalization therapy is based on the idea that tissue repair can take place similarly to devitalized, uninfected, avulsed, immature permanent teeth if there are no bacteria present, a suitable three-dimensional scaffold, stem/progenitor cells, and a bacteria-tight seal formed inside the root canal space. When it comes to revascularization, three things need to be taken into account: (i) cleaning the root canal system; (ii) providing a scaffold; and (iii) coronal sealing. The root canal system is most frequently reported to be disinfected with an irrigation solution of sodium hypochlorite (NaOCl) and chlorhexidine, followed by an antimicrobial dressing calcium hydroixde (Ca(OH)2) or antibiotic paste).
This review focuses on the current concepts on revascularization and procedures when performed under current protocols have reportedly achieved successful clinical and radiographical outcomes for immature permanent teeth with non-vital pulps and its efficacy as Regenerative Endodontic Procedure
Keywords: Regenerative endodontic procedures, pulp regeneration, growth factors, apical canals
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References
Pollyana Rodrigues de Souza Araújo, Luciano Barreto Silva, Alexandrino Pereira dos Santo Sampaio, Pulp Revascularization: A Literature Review Open Dentistry Journal; 2017.
Maria Tereza Pedrosa Albuquerque, Juliana Yuri Nagata, Adriana de Jesus Soares, Alexandre Augusto Zaia, Pulp revascularization: An alternative treatment to the apexification of immature teeth odontol; 2014.
Mélanie namour and stephanie theys, review article- pulp revascularization of immature permanent teeth: A ReviewOf the Literature and a Proposal of a New Clinical Protocol, Scientific World Journal; 2014
Sabrosa CE, Geber K, Chagas B. The use of a preformed composite resin crown to treat molar incisor hypomineralization: A Clinical Report. Int. J. Res. Rep. Dent. 2020;3(1):44-9. Accessed On:2024 Jun. 2 Available:https://journalijrrd.com/index.php/IJRRD/article/view/45
Rao BS, Bandekar S, Kshirsagar S, Naman S. Endocrown-A Unique Way of Retention-Case Report. J. Adv. Med. Med. Res. 2017 ;22(3):1-5. Accessed On:2024 Jun. 2 Available:https://www.journaljammr.com/index.php/JAMMR/article/view/3049
Bhuva B, Giovarruscio M, Rahim N, Bitter K, Mannocci F. The restoration of root filled teeth: A review of the clinical literature. International Endodontic Journal. 2021;54 (4):509-35.
Zhang W, Yelick PC, Vital pulp therapy-current progress of dental pulp regeneration and revascularization, Int J Dent; 2010.
Garcia-Godoy F, PE, Recommendations for using regenerative endodontic procedures in permanent immature traumatized teeth, Dent Traumatol; 2012.
Acta , The role of blood clot in endodontic therapy: An experimental histologic study Odontol Scand; 1961.
Banchs F, Trope M, Revascularization of immature permanent teeth with apical periodontitis: New treatment protocol J Endod; 2004.
Gözde Kotan Betül Aycan Alim. A Review of Regenerative Endodontics, Dental and Medical Journal; 2020.
Manoj Kumar Pulyodan , Sunil Paramel Mohan , Dhanya Valsan , Namitha Divakar , Shabna Moyin , Shamsheer Thayyil Regenerative Endodontic: A Paradigm Shift In Clinical Endodontics
J Pharm Bioallied Sci; 2020.
Kim SG, Malek M, Sigurdsson A, Lin LM. Kahler B. Regenerative endodontics: A comprehensive review ,Int Endod J; 2018
Murray PE, Review of guidance for the selection of regenerative endodontics, apexogenesis, apexification, pulpotomy, and other endodontic treatments for immature permanent teeth, Int Endod J; 2023.
Patil Anand N, Karkare Swati R, Damade Yogesh, Puri Juhi, Patil Saylee , Pulp Revascularization: A Review, International Journal of Medical Science and Dental Research; 2020.
Plascencia H, Díaz M, Gascón G, Garduño S, Guerrero-Bobadilla C, Márquez-De Alba S, González-Barba G, Management of permanent teeth with necrotic pulps and open apices according to the stage of root development Journal of Clinical and Experimental Dentistry; 2017.
Reynolds K, Johnson JD, Cohenca N. Pulp revascularization of necrotic bilateral bicuspids using a modified novel technique to eliminate potential coronal discolouration: a case report, International Endodontic Journal; 2009.
Rohit Pannu, Pulp revascularization - An evolving concept: A review International Journal of Applied Dental Sciences; 2017.
Xi Wei, Maobin Yang, Lin Yue, Dingming Huang, Xuedong Zhou, Xiaoyan Wang, Qi Zhang, Lihong Qiu, Zhengwei Huang, Expert consensus on regenerative endodontic procedures review article, International Journal of Oral Science; 2022.
AAE Clinical Considerations for a Regenerative Procedure. Revised; 5/18/2021
Justyna Zbanska, Katarzyna Herman, Piotr Kuropka, Maciej Dobrzy, Review Regenerative Endodontics as the Future Treatment of Immature Permanent Teeth Journal of Appl. Sci; 2021.
Tugba Bezgin, Hayriye S€onmez, Review of current concepts of revascularization/revitalization, Dent Traumatol; 2015.
Nassar M, Hiraishi N, Tamura Y, Otsuki M, Aoki K, Tagami , Phytic acid: An Alternative Root Canal Chelating Agent, J Endod; 2015.
Ruparel F, Teixeira R, Ferraz. Direct effect of intracanal medicaments on survival of stem cells of the apical papilla. Diogenes Journal of Endodontics; 2012.
Lin LM, Rosenberg PA., Repair and regeneration in endodontics. Int Endod J ; 2011
Murray PE, Garcia-Godoy F, Hargreaves KM. Regenerative endodontics: a review of current status and a call for action, J Endod. 2007
Hargreaves KM, Law AS Hargreaves KM, Cohen S, editors. Regenerative endodontics Cohen’s pathways of the pulp. 10th ed. St. Louis, MO: Mosby Elsevier; 2011.
Rule DC, Winter GB, Root growth and apical repair subsequent to pulpal necrosis in children Dent J; 1966.
Mrunali G, Gharat, Amit Patil, Pooja Yadav, Ashish K Jain, Sheetal Mali, Shruti Singh. Pulp revascularization: A Boon for Future Therapy in Young Permanent Teeth, Oral Maxillofacial Pathology J; 2024.
Ham JW, Patterson WW, Mitchell DF. Induced apical closure of immature pulpless teeth in monkeys. Oral Surg Oral Med Oral Pathol; 1972.
Iwaya S, Ikawa M. Revascularization of a tooth with apical periodontitis and a sinus tract Dent Traumatol; 2001.
Windley W, Teixeira F, Levin L, Sigurdsson A, Trope M , Disinfection of immature teeth with a triple antibiotic paste Journal of Endodontics; 2005.