Outcome of Azithromycin with Non-Surgical Periodontitis Therapy at Dental Hospital, University of Health Sciences, Lao PDR
Published: 2024-08-23
Page: 291-295
Issue: 2024 - Volume 7 [Issue 1]
Khouaxiong Xiaze *
Department of Restorative in Dentistry, University of Health Sciences, Lao PDR.
Chanthavisao Phanthanalay
Department of Restorative in Dentistry, University of Health Sciences, Lao PDR.
Bounsong Boutsamphanh
Department of Restorative in Dentistry, University of Health Sciences, Lao PDR.
Daovone Homboutsavong
Department of Restorative in Dentistry, University of Health Sciences, Lao PDR.
Xayyaphon Latsomphou
Department of Restorative in Dentistry, University of Health Sciences, Lao PDR.
Soutsada Songphadith
Department of Restorative in Dentistry, University of Health Sciences, Lao PDR.
Thiphavanh Vongxay
Department of Restorative in Dentistry, University of Health Sciences, Lao PDR.
Soulideth Inthakone
Department of Restorative in Dentistry, University of Health Sciences, Lao PDR.
Alouna Vilaylack
Department of Restorative in Dentistry, University of Health Sciences, Lao PDR.
Fongsamouth Doungnouvong
Department of Restorative in Dentistry, University of Health Sciences, Lao PDR.
Phimfalee Sayaxang
Department of Dental Basic Sciences in Dentistry, University of Health Sciences, Lao PDR.
Phoutthasone Thiphukdy
Division of Dental Clinic in Dentistry, University of Health Sciences, Lao PDR.
*Author to whom correspondence should be addressed.
Abstract
Objective: The study aimed to evaluate the effectiveness of Azithromycin as an adjunct to non-surgical periodontal therapy.
Methods: This is a cross-sectional descriptive study. The subjects were divided into two equal groups (Group study and Group control). At baseline, patients received a full-mouth supra scaling with an ultrasonic scaler, scaling, and root planing in sites with probing depths >4 mm, and were placed on a systemic antibiotic regimen: Azithromycin 250 mg (Group study) and doxycycline 250 mg (Group control), all groups once a day for 5 days. The subjects were recalled at day 5, day 30, and day 90.
Results: The comparison of the outcome of periodontitis treatment with Azithromycin 250 mg and doxycycline 250 mg, evaluated by plaque index and clinical attachment loss, showed significant differences between the groups. The clinical parameters were different from the baseline values.
Conclusion: Azithromycin 250 mg with non-surgical periodontitis therapy was significant.
Keywords: Azithromycin 250 mg with non-surgical periodontitis therapy, Lao PDR