Asian Journal of Dental Sciences <p style="text-align: justify;"><strong>Asian Journal of Dental Sciences</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AJDS/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;‘Dental research’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> en-US (Asian Journal of Dental Sciences) (Asian Journal of Dental Sciences) Mon, 28 Oct 2019 08:54:30 +0000 OJS 60 Periostin: A Potential Biomarker for Periodontitis <p><strong>Background: </strong>Periostin is among the most important extracellular matrix proteins, that seems to play a role in the healing of periodontal defects as a modulator of periodontal ligament (PDL) hemostasis. This study aims to review the available literature on this protein and its role in the healing of periodontal defects.&nbsp;</p> <p><strong>Methods: </strong>An electronic search of the literature was carried out in PubMed and Google Scholar using the keywords “periostin”, “gingival crevicular fluid”, “saliva” and “periodontitis”.</p> <p><strong>Results:</strong> Periostin, as an extracellular matrix protein, was found to play a key role as a modulator of critical cellular interactions in disease conditions. It is necessary for tissue integrity and plays a critical role in wound healing.</p> <p><strong>Conclusion:</strong> The role of periostin in cell proliferation, differentiation, migration and signalling to maintain hemostasis has yet to be identified. Further studies are warranted in this respect.</p> Zeinab Rezaei Esfahrood, Setareh Kazemi Veysari ##submission.copyrightStatement## Mon, 28 Oct 2019 00:00:00 +0000